UNII Codes

UNII codes provide unique identifiers for ingredients. See UNII Codes Questions and Answers for answers to some commonly raised questions.

(provided by the SRS group at FDA)


Example:
AMPHOTERICIN B has a UNII code of 7XU7A7DROE.

For SPL, they appear as part of the <activeIngredientSubstance> coding:

<activeIngredientSubstance>
<code code="I1T8O1JTL6" codeSystem="2.16.840.1.113883.4.9" codeSystemName="FDA SRS" />
<name>prochlorperazine maleate</name>
<activeMoiety>
<activeMoiety>
<code code="YHP6YLT61T" codeSystem="2.16.840.1.113883.4.9" codeSystemName="FDA SRS" />
<name>prochlorperazine</name>
</activeMoiety>
</activeMoiety>
</activeIngredientSubstance>

These codes are assigned by <insert reference here>

The FDA posts updates to the UNII code list on the Data Council Standards page. These updates show up frequently -- check back often.

Searchable UNIIs Database

Website to search a web-based database for unique ingredient identifiers (UNIIs):
http://fdasis.nlm.nih.gov
.

Other Locations for UNIIs

• Inactive Ingredients look-up: http://www.accessdata.fda.gov/scripts/cder/iig/index.cfm
• The UNII has been adopted by the United States Consolidated Health Informatics initiative http://www.hhs.gov/healthit/chiinitiative.html; http://www.hhs.gov/healthit/documents/chiinitiative/med_ingred_full_public.pdf
• The UNII is recommended by the National Committee on Vital and Health Statistics http://ncvhs.hhs.gov/031105lt2.pdf at page 8
• UNIIs have been incorporated into the VA's National Drug File Reference Terminology (NDF-RT), which in turn is available through NLM's Unified Medical Language System (UMLS) http://www.nlm.nih.gov/research/umls/metab2.html.
• UNIIs have been incorporated into the National Cancer Institutes Enterprise Vocabulary Service http://www.cancer.gov/cancertopics/terminologyresources/page5
• UNIIs will be incorporated into the electronic version of the 2007 edition of the USP Dictionary of USAN and International Drug Names http:// www.usp.org/products/dictionary/, as well as subsequent printed versions.
• UNIIs will be assigned to each substance that is in the Environmental Protection Agency's Substance Registry System http://www.epa.gov/srs/index.htm.

Substance Registration System (SRS)

SRS User Guide